Zika virus and assay development for screening
In collaborative projects, SCTL scientist study important questions around Zika virus (ZIKV) biology such as identifying new receptors that render human neural stem cells vulnerable to infection. The...
View ArticleControlled differentiation of iPSCs into ectodermal, mesodermal, and...
The overarching objective of this project is to delineate how iPSCs exit the pluripotent state and differentiate into the three primary germ layers (ectoderm, mesoderm, endoderm). SCTL scientists...
View ArticleAutomated iPSC culture
The overarching objective of this project is to delineate how iPSCs exit the pluripotent state and differentiate into the three primary germ layers (ectoderm, mesoderm, endoderm). SCTL scientists...
View ArticleSingle-cell RNA analysis of iPSCs and differentiated progeny
Three single-cell systems- 10X Genomics Chromium, BioRad ddSeq, and Fluidigm C1 – are being used to characterize different iPSC lines and differentiated cell types for subsequent Illumina NextSeq RNA...
View ArticleCollaborations with SCTL
SCTL is focused on addressing the key biological and technological roadblocks that impede the translation of iPSC into clinical and regenerative medicine applications. Toward this mission, SCTL is...
View ArticleNIH Common Fund original goals for SCTL
Bring iPSC-derived cells closer to clinical applications Establish QC standards to define pluripotency and differentiated cell types Develop methods to assess heterogeneity and characterize...
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